Sugar acids and derivatives
Medchemexpress LLC IL-1RA/IL-1F3 Porci 10ug | 10ug
IL-1RA/IL-1F3 proteins are powerful anti-inflammatory antagonists in the interleukin 1 family specifically targeting the pro-inflammatory cytokines IL1B and IL1A This protein counteracts the inflammatory effects of IL1 playing a critical role in preventing immune dysregulation and preventing uncontrolled systemic inflammation triggered by a variety of innate irritants including pathogens IL-1RA/IL-1F3 Protein Porcine is the recombinant Porcine-derived IL-1RA/IL-1F3 protein expressed by E coli with tag free
Alkali Scientific D Glucuronic Acid Sodium Salt Monohydrate, 100 G
D Glucuronic Acid Sodium Salt Monohydrate is a high-quality biochemical reagent, available in a 100-gram quantity for larger-scale laboratory applications. This reagent is crucial for research involving carbohydrate metabolism, glycosylation, and the synthesis of glycosaminoglycans. Glucuronic acid is a fundamental building block in many biological processes, particularly in detoxification reactions where it forms conjugates to increase water solubility. It is used in both academic and industrial laboratories for its role in the biosynthesis of complex carbohydrates and as a substrate in enzymatic reactions. The sodium salt monohydrate form provides excellent solubility and stability in aqueous solutions.
Medchemexpress LLC 4-methylumbelliferyl stearate | 79408-85-8 | MFCD00057311 | 99.0% | 442.63 g/mol | C28H42O4 | 250 MG
4-Methylumbelliferyl stearate is a fluorogenic biochemical reagent used as a substrate for esterase and lipase assays. Enzymatic hydrolysis releases the fluorescent 4-methylumbelliferone (4-MU), enabling sensitive, quantitative measurement of enzyme activity in biochemical and cell-based research. For research use only.
- Releases fluorescent 4-methylumbelliferone upon hydrolysis.
- Enables sensitive, quantitative enzyme activity assays.
- Suitable for esterase and lipase substrate assays.
- Available in multiple sample sizes for assay optimization.
- Stable when stored sealed at room temperature.
- Supplied with purity and batch certificate information.
Medchemexpress LLC Chmfl-pi4k-127 | 2377604-81-2 | 99.9% | 402.85 g/mol | C18H15ClN4O3S | 10 MG
CHMFL-PI4K-127 is a potent, selective Plasmodium falciparum phosphatidylinositol 4-kinase (PfPI4K) inhibitor provided for research use. It exhibits sub-nanomolar enzymatic potency and cellular antimalarial activity, and is supplied at high chemical purity suitable for in vitro and in vivo studies.
- Potent PfPI4K inhibition (IC50 ~0.9 nM).
- Demonstrated cellular antimalarial activity (EC50 ~25.1 nM).
- High chemical purity for reliable experimental results (>99.9%).
- Available in research-scale quantities for assay development.
- Soluble in DMSO for standard compound handling and dosing.
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 50 MG
Glucuronic acid sodium is a polysaccharide that shows anti-inflammatory activity, helps heal ulcerative colitis, and improves the intestinal barrier by increasing tight junction proteins like ZO-1 and Occludin. It also modifies gut microbiota by increasing beneficial bacteria and suppressing harmful ones.
- Shows anti-inflammatory activity
- Helps heal ulcerative colitis
- Improves intestinal barrier by increasing tight junction proteins like ZO-1 and Occludin
- Modifies gut microbiota by increasing beneficial bacteria and suppressing harmful ones
Medchemexpress LLC PROTAC BET Degrader-10 | 1957234-97-7 | 99.39% | 783.29 | 25 MG
PROTAC BET Degrader-10 (dBET37) is a potent BET protein BRD4 degrader, connected by ligands for Cereblon and BRD4, with a DC50 of 49 nM. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Potent BET protein BRD4 degrader
- Connects ligands for Cereblon and BRD4
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Interferon alpha/beta receptor 1 Antibody (YA3833) | 110-130 kDa | 10 UL
This Interferon alpha/beta receptor 1 Antibody (YA3833) is a mouse-derived, non-conjugated IgG1 monoclonal antibody targeting Interferon alpha/beta receptor 1. It forms a heterodimeric receptor with IFNAR2 for type I interferons, activating the JAK-STAT signaling cascade to regulate interferon-responsive genes.
- Mouse-derived monoclonal antibody
- Non-conjugated IgG1 isotype
- Targets interferon alpha/beta receptor 1
- Reacts with human and mouse species
- Suitable for WB, IHC-P, FC, and ELISA applications
- Supplied as a liquid in PBS with 0.05% sodium azide
- Purity is affinity purified
- Store at -20°C for one year; avoid repeated freeze/thaw cycles
![Alkali Scientific 4 Methylumbelliferyl 2 acetamido 2 deoxy B D glucopyranoside [4 Methylumbelliferyl N acetyl B D glucosaminide], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660605.jpg-250.jpg)
Alkali Scientific 4 Methylumbelliferyl 2 acetamido 2 deoxy B D glucopyranoside [4 Methylumbelliferyl N acetyl B D glucosaminide], 1 G
Methylumbelliferyl N-acetylglucosaminide (1 g) is a fluorogenic substrate used in enzymatic assays, particularly for detecting the activity of β-glucosaminidases. This compound is widely used in research and diagnostic laboratories for assessing enzyme activity in microbial samples, tissue cultures, and various biochemical processes. The fluorogenic property of this substrate means it generates a detectable fluorescence when cleaved by the enzyme, providing a sensitive and reliable measurement. This 1 g quantity is ideal for routine laboratory assays where the activity of glycosidases, particularly in cell-based systems, is being studied.
Medchemexpress LLC D-Glucuronic acid sodium salt monohydrate | 207300-70-7 | 5 G
D-Glucuronic acid sodium salt monohydrate is a primary constituent of various anti-inflammatory proteoglycans. It has the ability to promote embryonic development and inhibit cell aggregation. Upon metabolization into ethyl glucuronide, it activates Toll-like receptor 4 (TLR4), which can lead to pain. Both D-Glucuronic acid sodium salt monohydrate and its derivative, glucurono-lactone, can serve as liver detoxifiers for human health prevention, and its derivatives also demonstrate anti-tumor activity. The product has a purity of 98.0% and is intended for research use only.
- Promotes embryonic development and inhibits cell aggregation
- Activates Toll-like receptor 4 (TLR4)
- Functions as a liver detoxifier
- Demonstrates anti-tumor activity (derivatives)
- Intended for research use only
- High purity
Medchemexpress LLC Integrin alpha V bet 5ug
Integrin V beta 5 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 8 Protein Human (HEK293 His solution) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 8 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 8 Protein Human (HEK293 His solution) has molecular weight of 187 95 kDa
Medchemexpress LLC Insulin Receptor Beta Antibody (YA341) | Protein A affinity purified | Predicted band size: 156 kDa; Observed band size: 95 kDa | 10 UL
Insulin Receptor Beta Antibody (YA341) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Insulin Receptor Beta. This antibody is developed for research use only and mediates the pleiotropic actions of insulin, playing a key role in cell growth, survival, and differentiation.
- Host: rabbit
- Clonality: recombinant, monoclonal
- Species reactivity: human, rat
- Immunogen: synthetic peptide corresponding to human insulin receptor (AA range: 930-970)
- Applications: WB (1:500-1:2000), ICC/IF (1:100-1:500)
- Purity: protein A affinity purified
- Conjugation: non-conjugated
- Formulation: supplied in 1*TBS (pH7.4), 0.05% BSA, 40% glycerol, and 0.05% sodium azide
- Storage: stored at -20°C for 1 year; avoid repeated freeze/thaw cycles
- Shipping: shipped with blue ice
Alkali Scientific Leupeptin Hemisulfate, 1 Milligram
Leupeptin Hemisulfate is a potent protease inhibitor available in a 1-milligram quantity. It is primarily used in biochemical research to inhibit serine, cysteine, and threonine proteases. Leupeptin is commonly employed to prevent proteolysis in experiments involving protein isolation, enzyme assays, and cell culture studies. By inhibiting a wide range of proteases, Leupeptin preserves the integrity of proteins during their extraction and purification processes. This reagent is essential for studies focusing on enzyme activity, protein-protein interactions, and various cellular mechanisms in both in vitro and in vivo research applications.
Medchemexpress LLC Integrin alpha V bet 20ug | 20ug
Integrin alpha V beta 3 (ITGAV ITGB3) functions as a receptor for CD40LG enhancing Lilrb4a inhibitory effects on mast cell activation It suppresses marginal zone B cell antibody production through Lilrb4a interaction ITGAV ITGB3 forming a heterodimer with ITGAV interacts with ligands such as RAB25 CIB1 FBLN5 and more It also forms a complex with PTPRZ1 and PTN stimulating endothelial cell migration Integrin alpha V beta 6 Protein Mouse (HEK293 His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 6 Protein Mouse (HEK293 His) has molecular weight of 90-140 kDa
Medchemexpress LLC Homo-PROTAC pVHL30 degrader 1 | 2244684-49-7 | 99.4% | 1179.45 | 25 MG
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC, consisting of two ligands of von Hippel-Lindau. It dimerizes von Hippel-Lindau (VHL) with high avidity in vitro and induces potent, rapid, and proteasome-dependent self-degradation of VHL in different cell lines, in a highly isoform-selective fashion and without triggering a hypoxic response. This product is for research use only.
- Dimerizes von Hippel-Lindau (VHL) with high avidity in vitro.
- Induces potent, rapid and proteasome-dependent self-degradation of VHL in different cell lines.
- Acts in a highly isoform-selective fashion.
- Does not trigger a hypoxic response.
Medchemexpress LLC Integrin alpha V bet 50ug | 50ug
Integrin alpha V beta 6 Protein Human (HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His C-Avi labeled tag Integrin alpha V beta 6 Protein Human (HEK293 His-Avi) has molecular weight of 90-150 kDa